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ALLERGY


Dr Gugenheim


The word "allergy" was coined by the Viennese pediatrician Clemens von Pirquet in 1906. Pirquet noted that some of his patients were hypersensitive to normally innocuous entities such as dust, pollen, or certain foods. He called this phenomenon "allergy", from the Greek words allos meaning "other" and ergon meaning "work". Historically, all forms of hypersensitivity were classified as allergies, and all thought to be caused by an improper activation of the antibody class called Immunoglobulin E - Teruka and Kimishige Ishizaka were among the first to isolate and describe IgE in the 1960s. Later, it became clear that several different disease mechanisms were implicated, with the common link between these varying hypersensitivities being a disordered activation of the immune system in one way or another. A new classification scheme was designed by P. Gell and R. Coombs to reflect what were then rebaptized hypersensitivity reactions. The word "allergy" was then restricted to type I hypersensitivities, which are caused by the classical IgE mechanism.

 
DoctorsOffice Number
Stephen Gugenheim, MD940-766-8772


Your ENT Doctor will schedule you a time with the Allergy Department.



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